1 Corinthians 1:26-29

Not many wise men after the flesh. Paul now shows the weakness of the human instrumentality chosen to convert the world; not those the world called wise, not the mighty, not the noble, yet the work was moving on with wonderful power. But God hath chosen the foolish things of the world. Men whom the world would call foolish, with a gospel that it called foolishness; yet these "confounded the wise" and upturned the world's philosophies. Base things of the world. Those of lowly birth.

And things which are despised. People that the world would call "nobodies", and things that it counts as nothing. These are chosen to bring to nothing things that are; the existing state of things; the pagan religious, governments, and civilization; these were to be overthrown through the influence of the gospel.
That no flesh should glory in his presnece. That it should be shown that the power was of God.
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